NP_037150.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ras-related protein Rab-3A
NCBI Official Synonym Full Names
RAB3A, member RAS oncogene family
NCBI Official Synonym Symbols
NCBI Protein Information
ras-related protein Rab-3A; Ras-related small GTP binding protein 3A
UniProt Protein Name
Ras-related protein Rab-3A
UniProt Entry Name
RAB3A_RAT
NCBI Summary for RAB3A
regulated synaptic vesicle endocytosis [RGD, Feb 2006]
UniProt Comments for RAB3A
Function: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal
By similarity.
Subunit structure: Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3AL. Interacts with the exocyst complex through SEC15. Binds SYTL4 and RIMS1. Interacts with SGSM1 and SGSM3
By similarity. Heterodimer with RIMS2. Interacts with RPH3A. Interacts with RAB3IP. Ref.4 Ref.5 Ref.6
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side
Potential.
Tissue specificity: Detected in brain.
Sequence similarities: Belongs to the small GTPase superfamily. Rab family.
Product References and Citations for anti-RAB3A antibody
• Schluter OM, Schmitz F, Jahn R, Rosenmund C, Sudhof TC (2004) A Complete Genetic Analysis of Neuronal Rab3 Function. J Neuroscience 24(29):6629-6637 • Schluter OM, Basu J, Sudhof TC, Rosenmund C (2006) Rab3 Superprimes Synaptic Vesicles for Release: Implications for Short-term Synaptic Plasticity. J Neuroscience 26(4):1239-1246. • Coppola T, Perret-Menoud V, Gattesco S, Magnin S, Pombo I, Blank U, Regazzi R (2002) The death domain of Rab3 guanine nucleotide exchange protein in GDP/GTP exchange activity in living cells. J Biochem 362 (Pt.2):273-9.
Research Articles on RAB3A
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Pathways associated with anti-RAB3A antibody
Diseases associated with anti-RAB3A antibody
Organs/Tissues associated with anti-RAB3A antibody
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