NP_004253.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
46,263 Da
NCBI Official Full Name
transmembrane protease serine 11D
NCBI Official Synonym Full Names
transmembrane protease, serine 11D
NCBI Official Synonym Symbols
NCBI Protein Information
transmembrane protease serine 11D
UniProt Protein Name
Transmembrane protease serine 11D
UniProt Synonym Protein Names
Airway trypsin-like protease
UniProt Synonym Gene Names
UniProt Entry Name
TM11D_HUMAN
NCBI Summary for TMPRSS11D
This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008]
UniProt Comments for TMPRSS11D
TMPRSS11D: May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Belongs to the peptidase S1 family.
Protein type: EC 3.4.21.-; Membrane protein, integral; Protease
Chromosomal Location of Human Ortholog: 4q13.2
Cellular Component: extracellular region; integral to plasma membrane
Molecular Function: peptidase activity; serine-type endopeptidase activity
Biological Process: proteolysis; respiratory gaseous exchange
Research Articles on TMPRSS11D
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Diseases associated with anti-TMPRSS11D antibody
Organs/Tissues associated with anti-TMPRSS11D antibody
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