NP_063947.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,786 Da
NCBI Official Full Name
transmembrane protease serine 4 isoform 1
NCBI Official Synonym Full Names
transmembrane protease, serine 4
NCBI Protein Information
transmembrane protease serine 4
UniProt Protein Name
Transmembrane protease serine 4
UniProt Synonym Protein Names
Channel-activating protease 2; CAPH2; Membrane-type serine protease 2; MT-SP2
UniProt Synonym Gene Names
UniProt Entry Name
TMPS4_HUMAN
NCBI Summary for TMPRSS4
This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for TMPRSS4
TMPRSS4: Probable protease. Seems to be capable of activating ENaC. Belongs to the peptidase S1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; EC 3.4.21.-; Protease
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: integral to membrane
Molecular Function: protein binding; scavenger receptor activity; serine-type endopeptidase activity
Biological Process: proteolysis; receptor-mediated endocytosis
Research Articles on TMPRSS4
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Products associated with anti-TMPRSS4 antibody
Pathways associated with anti-TMPRSS4 antibody
Diseases associated with anti-TMPRSS4 antibody
Organs/Tissues associated with anti-TMPRSS4 antibody
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