NP_008881.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
70,033 Da
NCBI Official Full Name
synapsin-1 isoform Ia
NCBI Official Synonym Full Names
synapsin I
NCBI Protein Information
synapsin-1
UniProt Protein Name
Synapsin-1
UniProt Synonym Protein Names
Brain protein 4.1; Synapsin I
NCBI Summary for SYN1
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for SYN1
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
Product References and Citations for anti-SYN1 antibody
Diviya Sinha, et, al. (2005) Am J Physiol Renal Physiol; 288: F703-F713. Franco Onofri, et, al. (2000) J. Biol. Chem; 275: 29857. Dario Bonanomi, et, al. (2005) J. Neurosci; 25: 7299-7308. Hiroshi Tokumitsu, et, al. (2005) J. Biol. Chem; 280: 35108-35118.
Research Articles on SYN1
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Products associated with anti-SYN1 antibody
Pathways associated with anti-SYN1 antibody
Diseases associated with anti-SYN1 antibody
Organs/Tissues associated with anti-SYN1 antibody
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