NP_055211.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
vacuolar protein sorting-associated protein 41 homolog isoform 1
NCBI Official Synonym Full Names
vacuolar protein sorting 41 homolog (S. cerevisiae)
NCBI Protein Information
vacuolar protein sorting-associated protein 41 homolog; S53; vacuolar assembly protein 41
UniProt Protein Name
Vacuolar protein sorting-associated protein 41 homolog
UniProt Synonym Protein Names
S53
UniProt Entry Name
VPS41_HUMAN
NCBI Summary for VPS41
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq, Jul 2008]
UniProt Comments for VPS41
VPS41: Required for vacuolar assembly and vacuolar traffic. Belongs to the VPS41 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system; Vesicle
Chromosomal Location of Human Ortholog: 7p14-p13
Cellular Component: microtubule cytoskeleton; membrane; lysosomal membrane; early endosome; late endosome; Golgi-associated vesicle; cytosol
Molecular Function: GTPase binding; protein binding; zinc ion binding; microtubule binding
Biological Process: vesicle-mediated transport; protein targeting to vacuole; vacuole fusion, non-autophagic; Golgi vesicle transport
Research Articles on VPS41
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Products associated with anti-VPS41 antibody
Diseases associated with anti-VPS41 antibody
Organs/Tissues associated with anti-VPS41 antibody
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