NP_002187
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
52,923 Da
NCBI Official Full Name
insulinoma-associated protein 1
NCBI Official Synonym Full Names
insulinoma-associated 1
NCBI Official Synonym Symbols
NCBI Protein Information
insulinoma-associated protein 1; zinc finger protein IA-1
UniProt Protein Name
Insulinoma-associated protein 1
UniProt Synonym Protein Names
Zinc finger protein IA-1
UniProt Synonym Gene Names
UniProt Entry Name
INSM1_HUMAN
NCBI Summary for INSM1
Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors. [provided by RefSeq, Jul 2008]
UniProt Comments for INSM1
INSM1: May be associated with the transformation of neuroendocrine cells.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 20p11.2
Cellular Component: nucleoplasm; transcriptional repressor complex; nucleus
Molecular Function: cyclin binding; chromatin DNA binding; metal ion binding; histone deacetylase binding; transcription factor activity
Biological Process: norepinephrine biosynthetic process; negative regulation of cell proliferation; negative regulation of protein amino acid phosphorylation; transcription, DNA-dependent; regulation of gene expression; regulation of protein complex assembly; negative regulation of transcription from RNA polymerase II promoter; cell cycle; positive regulation of cell differentiation; endocrine pancreas development
Research Articles on INSM1
Precautions
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Disclaimer
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Products associated with INSM1 blocking peptide
Pathways associated with INSM1 blocking peptide
Diseases associated with INSM1 blocking peptide
Organs/Tissues associated with INSM1 blocking peptide
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