AAH09401
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,003 Da
NCBI Official Full Name
IL32 protein
NCBI Official Synonym Full Names
interleukin 32
NCBI Official Synonym Symbols
NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma [Similar Products]
NCBI Protein Information
interleukin-32; interleukin-32 eta; interleukin-32 small; interleukin-32 theta; natural killer cells protein 4; natural killer cell transcript 4; tumor necrosis factor alpha-inducing factor
UniProt Protein Name
Interleukin-32
UniProt Synonym Protein Names
Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor
UniProt Synonym Gene Names
UniProt Entry Name
IL32_HUMAN
NCBI Summary for IL32
This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
UniProt Comments for IL32
IL32: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF- alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: extracellular space; membrane
Molecular Function: protein binding; cytokine activity
Biological Process: immune response; defense response; cell adhesion
Research Articles on IL32
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Disclaimer
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Products associated with IL32 blocking peptide
Diseases associated with IL32 blocking peptide
Organs/Tissues associated with IL32 blocking peptide
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