NP_001002889.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
112,800 Da
NCBI Official Full Name
nucleotide-binding oligomerization domain-containing protein 2
NCBI Official Synonym Full Names
nucleotide-binding oligomerization domain containing 2<
NCBI Official Synonym Symbols
NCBI Protein Information
nucleotide-binding oligomerization domain-containing protein 2; caspase recruitment domain 15 protein; caspase recruitment domain-containing protein 15
UniProt Protein Name
Nucleotide-binding oligomerization domain-containing protein 2
UniProt Synonym Protein Names
Caspase recruitment domain-containing protein 15
UniProt Synonym Gene Names
UniProt Entry Name
NOD2_BOVIN
UniProt Comments for NOD2
Function: Recognizes muramyl dipeptide (MDP) constituents of bacterial peptidoglycans and plays a key role in gastrointestinal immunity: upon stimulation, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling, leading to activate the transcription of hundreds of genes involved in immune response
Research Articles on NOD2
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Disclaimer
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Pathways associated with NOD2 elisa kit
Diseases associated with NOD2 elisa kit
Organs/Tissues associated with NOD2 elisa kit
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