NP_009117.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
274,380 Da
NCBI Official Full Name
centrosome-associated protein CEP250
NCBI Official Synonym Full Names
centrosomal protein 250kDa
NCBI Protein Information
centrosome-associated protein CEP250; 250 kDa centrosomal protein; centrosomal protein, 250-KD; centrosome associated protein; centrosomal Nek2-associated protein 1
UniProt Protein Name
Centrosome-associated protein CEP250
UniProt Synonym Protein Names
250 kDa centrosomal protein; Cep250; Centrosomal Nek2-associated protein 1; C-Nap1; Centrosomal protein 2
UniProt Synonym Gene Names
UniProt Entry Name
CP250_HUMAN
NCBI Summary for CEP250
This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. [provided by RefSeq, Jun 2009]
UniProt Comments for CEP250
CEP250: Probably plays an important role in centrosome cohesion during interphase. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 20q11.22
Cellular Component: centriole; centrosome; protein complex; perinuclear region of cytoplasm; microtubule organizing center; spindle pole centrosome; cytosol; cilium
Molecular Function: protein C-terminus binding; protein domain specific binding; protein binding; protein kinase binding
Biological Process: protein localization; regulation of centriole-centriole cohesion; protein localization in organelle; organelle organization and biogenesis; mitotic cell cycle; G2/M transition of mitotic cell cycle; centriole-centriole cohesion
Research Articles on CEP250
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Products associated with CEP250 elisa kit
Pathways associated with CEP250 elisa kit
Organs/Tissues associated with CEP250 elisa kit
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