AAH63851.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
93,518 Da
NCBI Official Full Name
Complement component 7
NCBI Official Synonym Full Names
complement component 7
NCBI Protein Information
complement component C7
UniProt Protein Name
Complement component C7
UniProt Entry Name
CO7_HUMAN
NCBI Summary for C7
C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008]
UniProt Comments for C7
C7: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Defects in C7 are a cause of complement component 7 deficiency (C7D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 5p13
Cellular Component: membrane attack complex; extracellular region
Biological Process: cellular sodium ion homeostasis; cytolysis; complement activation, alternative pathway; regulation of complement activation; innate immune response; complement activation, classical pathway; complement activation
Disease: Complement Component 7 Deficiency
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Products associated with C7 elisa kit
Pathways associated with C7 elisa kit
Diseases associated with C7 elisa kit
Organs/Tissues associated with C7 elisa kit
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