NP_006127.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,775 Da
NCBI Official Full Name
F-actin-capping protein subunit alpha-2
NCBI Official Synonym Full Names
capping protein (actin filament) muscle Z-line, alpha 2
NCBI Official Synonym Symbols
NCBI Protein Information
F-actin-capping protein subunit alpha-2; capZ alpha-2; F-actin capping protein alpha-2 subunit
UniProt Protein Name
F-actin-capping protein subunit alpha-2
UniProt Synonym Protein Names
CapZ alpha-2
UniProt Entry Name
CAZA2_HUMAN
NCBI Summary for CAPZA2
The protein encoded by this gene is a member of the F-actin capping protein alpha subunit family. It is the alpha subunit of the barbed-end actin binding protein Cap Z. By capping the barbed end of actin filaments, Cap Z regulates the growth of the actin filaments at the barbed end. [provided by RefSeq, Jul 2008]
UniProt Comments for CAPZA2
CAPZA2: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Belongs to the F-actin-capping protein alpha subunit family.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 7q31.2-q31.3
Cellular Component: cortical cytoskeleton; F-actin capping protein complex; membrane; extracellular region; cytosol; actin cytoskeleton
Molecular Function: actin binding
Biological Process: innate immune response; protein complex assembly; cell motility; barbed-end actin filament capping; blood coagulation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with CAPZA2 elisa kit
Pathways associated with CAPZA2 elisa kit
Diseases associated with CAPZA2 elisa kit
Organs/Tissues associated with CAPZA2 elisa kit
|