NP_001261418.1
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NCBI GenBank Nucleotide #
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UniProt Related Accession #
Molecular Weight
50,903 Da
NCBI Official Full Name
neurotrophin 1, isoform H
NCBI Official Synonym Full Names
Neurotrophin 1
NCBI Official Synonym Symbols
CG18318; CG32242; CG32244; CG42576; CT30097; DmelCG42576; dNT1; DNT1; spz2; Spz2 [Similar Products]
NCBI Protein Information
CG42576 gene product from transcript CG42576-RH; CG42576-PB; CG42576-PC; CG42576-PD; CG42576-PE; CG42576-PF; CG42576-PG; CG42576-PH; NT1-PB; NT1-PC; NT1-PD; NT1-PE; NT1-PF; NT1-PG; NT1-PH; drosophila Neurotrophin1; neurotrophin 1; spatzle 2; spz2
UniProt Protein Name
FI02176p
UniProt Synonym Protein Names
FI02176p; FI02376p; Neurotrophin 1 short isoform; Neurotrophin 1, isoform B; Neurotrophin 1, isoform C; Neurotrophin 1, isoform E
UniProt Synonym Gene Names
UniProt Entry Name
Q8IRB0_DROME
UniProt Comments for NT-1
Neurotrophin which may function as a ligand for the Toll-related receptors Toll-7 and Tollo (PubMed:22022271, PubMed:23892553). Binds to Toll-7 and probably acts as its ligand in promoting motor axon targeting and neuronal survival in the central nervous system (CNS) (PubMed:23892553). Involved in synaptic targeting of ISNb/d motorneurons and also some SNa motorneurons (PubMed:19018662). In larvae, involved in the negative regulation of the tracheal immune response to bacterial infection perhaps by acting as a ligand for the Toll-related receptor Tollo (PubMed:22022271). May be involved in the normal development of specific neurons at the neuromuscular junction (PubMed:24124519).
Research Articles on NT-1
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