NP_001264712.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,113 Da
NCBI Official Full Name
ubiquitin-like protein ATG12 isoform 2
NCBI Official Synonym Full Names
autophagy related 12
NCBI Protein Information
ubiquitin-like protein ATG12; Apg12 (autophagy, yeast) homolog; ATG12 autophagy related 12 homolog
UniProt Protein Name
Ubiquitin-like protein ATG12
UniProt Synonym Protein Names
Autophagy-related protein 12; APG12-like
UniProt Synonym Gene Names
UniProt Entry Name
ATG12_HUMAN
NCBI Summary for ATG12
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008]
UniProt Comments for ATG12
ATG12: Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5. Ubiquitous. Belongs to the ATG12 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin-like modifier; Autophagy
Chromosomal Location of Human Ortholog: 5q21-q22
Cellular Component: pre-autophagosomal structure membrane
Molecular Function: protein binding; APG8 conjugating enzyme activity
Biological Process: mitochondrion degradation; innate immune response; C-terminal protein lipidation; negative regulation of interferon type I production; autophagic vacuole formation; cellular response to nitrogen starvation
Research Articles on ATG12
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Products associated with ATG12 elisa kit
Pathways associated with ATG12 elisa kit
Diseases associated with ATG12 elisa kit
Organs/Tissues associated with ATG12 elisa kit
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