CAA07434.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
19,974 Da
NCBI Official Full Name
CAP1
NCBI Official Synonym Full Names
parkinson protein 7
NCBI Protein Information
protein DJ-1; fertility protein SP22; contraception-associated protein 1; parkinson disease protein 7 homolog; Parkinson disease (autosomal recessive, early onset) 7
UniProt Protein Name
Protein DJ-1
UniProt Synonym Protein Names
Contraception-associated protein 1; Protein CAP1; Fertility protein SP22; Parkinson disease protein 7 homolog
UniProt Synonym Gene Names
UniProt Entry Name
PARK7_RAT
NCBI Summary for CAP1
displays a specific localization pattern to the anterior-ventral surface of the equatorial segment; may play a role in sperm-egg interactions and fertilization [RGD, Feb 2006]
UniProt Comments for CAP1
DJ-1: associated with autosomal recessive early onset parkinsonism. Involved in the oxidative stress response. Three cysteines in DJ-1 may be oxidized to cysteine sulphonic acid in the cellular response to H2O2. Loss of DJ-1 function may lead to neurodegeneration.
Protein type: Tumor suppressor; Transcription regulation; Nuclear receptor co-regulator; EC 3.4.-.-
Cellular Component: PML body; mitochondrion; endoplasmic reticulum; axon; cytoplasm; plasma membrane; mitochondrial respiratory chain complex I; cytosol; nucleus; chromatin; lipid raft
Molecular Function: identical protein binding; oxidoreductase activity, acting on peroxide as acceptor; protein homodimerization activity; transcription coactivator activity; mercury ion binding; transcription factor binding; peptidase activity; mRNA binding; protein binding; enzyme binding; copper ion binding; androgen receptor binding; peroxiredoxin activity; cytokine binding; double-stranded DNA binding; glyoxalase III activity; superoxide dismutase copper chaperone activity; kinase binding; single-stranded DNA binding; receptor binding
Biological Process: synaptic transmission, dopaminergic; negative regulation of protein export from nucleus; adult locomotory behavior; protein deglycosylation; membrane hyperpolarization; proteolysis; glycolate biosynthetic process; positive regulation of interleukin-8 production; negative regulation of protein amino acid phosphorylation; regulation of mitochondrial membrane potential; single fertilization; regulation of neuron apoptosis; dopamine uptake; negative regulation of neuron apoptosis; negative regulation of protein binding; inflammatory response; response to drug; mitochondrion organization and biogenesis; protein stabilization; regulation of TRAIL receptor biosynthetic process; detoxification of copper ion; negative regulation of protein sumoylation; positive regulation of peptidyl-serine phosphorylation; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; methylglyoxal catabolic process to D-lactate; membrane depolarization; fertilization; response to hydrogen peroxide; detoxification of mercury ion; regulation of inflammatory response; hydrogen peroxide metabolic process; negative regulation of ubiquitin-protein ligase activity; lactate biosynthetic process; negative regulation of protein kinase activity; autophagy; positive regulation of transcription factor activity; negative regulation of protein ubiquitination; positive regulation of transcription from RNA polymerase II promoter; response to oxidative stress; negative regulation of apoptosis
Research Articles on CAP1
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Pathways associated with CAP1 elisa kit
Diseases associated with CAP1 elisa kit
Organs/Tissues associated with CAP1 elisa kit
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