NP_000827.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
143,752 Da
NCBI Official Full Name
glutamate receptor ionotropic, NMDA 2D
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
NCBI Protein Information
glutamate receptor ionotropic, NMDA 2D
UniProt Protein Name
Glutamate receptor ionotropic, NMDA 2D
UniProt Synonym Protein Names
EB11; Glutamate [NMDA] receptor subunit epsilon-4; N-methyl D-aspartate receptor subtype 2D; NMDAR2D; NR2D
UniProt Synonym Gene Names
UniProt Entry Name
NMDE4_HUMAN
NCBI Summary for GRIN2D
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq, Mar 2010]
UniProt Comments for GRIN2D
NMDAR2D: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2D/GRIN2D subfamily.
Protein type: Channel, ligand-gated; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: postsynaptic membrane; dendrite; plasma membrane; cell junction; N-methyl-D-aspartate selective glutamate receptor complex
Molecular Function: protein binding; extracellular-glutamate-gated ion channel activity; N-methyl-D-aspartate selective glutamate receptor activity
Biological Process: synaptic transmission, glutamatergic; synaptic transmission; startle response; ionotropic glutamate receptor signaling pathway; adult locomotory behavior; regulation of sensory perception of pain; signal transduction
Research Articles on GRIN2D
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Products associated with GRIN2D elisa kit
Pathways associated with GRIN2D elisa kit
Diseases associated with GRIN2D elisa kit
Organs/Tissues associated with GRIN2D elisa kit
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