AAA39288.1
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UniProt Secondary Accession #
Molecular Weight
30,723 Da
NCBI Official Full Name
interleukin 2 receptor, partial
UniProt Protein Name
Interleukin-2 receptor subunit alpha
UniProt Synonym Protein Names
p55; CD_antigen: CD25
UniProt Synonym Gene Names
Il2r; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA [Similar Products]
UniProt Entry Name
IL2RA_MOUSE
UniProt Comments for IL-2R
IL2RA: Receptor for interleukin-2. Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
Protein type: Membrane protein, integral
Cellular Component: cell surface; membrane; integral to membrane; external side of plasma membrane
Molecular Function: protein binding; interleukin-2 receptor activity; drug binding; interleukin-2 binding
Biological Process: regulation of T cell homeostatic proliferation; Notch signaling pathway; negative regulation of immune response; negative regulation of defense response to virus; positive regulation of activated T cell proliferation; negative regulation of lymphocyte proliferation; inflammatory response to antigenic stimulus; negative regulation of T cell proliferation; positive regulation of T cell differentiation; negative regulation of inflammatory response; T cell homeostasis; immune response; positive regulation of T cell proliferation; activated T cell apoptosis
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