AAA80608.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,335 Da
NCBI Official Full Name
macrophage inflammatory protein-1alpha
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 3
NCBI Protein Information
C-C motif chemokine 3; MIP-1-alpha; small inducible cytokine A3; small-inducible cytokine A3; macrophage inflammatory protein 1-alpha; Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3)
UniProt Protein Name
C-C motif chemokine 3
UniProt Synonym Protein Names
Macrophage inflammatory protein 1-alpha; MIP-1-alpha; Small-inducible cytokine A3
UniProt Synonym Gene Names
UniProt Entry Name
CCL3_RAT
NCBI Summary for MIP-1alpha
mediates monocyte and neutrophil chemotaxis; may play a role in the pathogenesis of acute lung injury [RGD, Feb 2006]
UniProt Comments for MIP-1alpha
Function: Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.
Subcellular location: Secreted.
Induction: By lipopolysaccharide (LPS).
Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.
Research Articles on MIP-1alpha
Precautions
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Disclaimer
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Pathways associated with MIP-1alpha elisa kit
Diseases associated with MIP-1alpha elisa kit
Organs/Tissues associated with MIP-1alpha elisa kit
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