NP_002584.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,972 Da
NCBI Official Full Name
procollagen C-endopeptidase enhancer 1
NCBI Official Synonym Full Names
procollagen C-endopeptidase enhancer
NCBI Protein Information
procollagen C-endopeptidase enhancer 1; procollagen C-proteinase enhancer 1; procollagen COOH-terminal proteinase enhancer 1; type 1 procollagen C-proteinase enhancer protein; type I procollagen COOH-terminal proteinase enhancer; procollagen, type 1, COOH-terminal proteinase enhancer
UniProt Protein Name
Procollagen C-endopeptidase enhancer 1
UniProt Synonym Protein Names
Procollagen COOH-terminal proteinase enhancer 1; PCPE-1; Procollagen C-proteinase enhancer 1; Type 1 procollagen C-proteinase enhancer protein; Type I procollagen COOH-terminal proteinase enhancer
UniProt Synonym Gene Names
UniProt Entry Name
PCOC1_HUMAN
NCBI Summary for PCPE1
Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008]
UniProt Comments for PCPE1
PCOLCE: Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.
Protein type: Secreted; Secreted, signal peptide; Extracellular matrix
Chromosomal Location of Human Ortholog: 7q22
Cellular Component: extracellular matrix; extracellular space
Molecular Function: collagen binding; heparin binding; protein binding; protease activator activity
Biological Process: multicellular organismal development; proteolysis
Research Articles on PCPE1
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Products associated with PCPE1 elisa kit
Pathways associated with PCPE1 elisa kit
Diseases associated with PCPE1 elisa kit
Organs/Tissues associated with PCPE1 elisa kit
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