NP_001262995.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
124,656 Da
NCBI Official Full Name
toll, isoform C
NCBI Official Synonym Full Names
Toll
NCBI Official Synonym Symbols
CG5490; CT17414; DmelCG5490; dToll; dToll1; EP(3)1051; EP1051; Fs(1)Tl; Fs(3)Tl; mat(3)9; mel(3)10; mel(3)9; T1; tl; TL; TOL; toll; toll-1; Toll-1; Toll1 [Similar Products]
NCBI Protein Information
CG5490 gene product from transcript CG5490-RB; CG5490-PB; CG5490-PC; CG5490-PD; EP1051; Tl-PB; Tl-PC; Tl-PD; Toll-1; protein toll precursor; toll receptor
UniProt Protein Name
Protein toll
UniProt Synonym Gene Names
UniProt Entry Name
TOLL_DROME
UniProt Comments for TLR-3
Receptor for the cleaved activated form of spz, spaetzle C-106 (PubMed:12872120). Binding to spaetzle C-106 activates the Toll signaling pathway and induces expression of the antifungal peptide drosomycin (PubMed:12872120, PubMed:8808632, PubMed:10973475). Component of the extracellular signaling pathway that establishes dorsal-ventral polarity in the embryo (PubMed:3931919). Promotes heterophilic cellular adhesion (PubMed:2124970). Involved in synaptic targeting of motoneurons RP5 and V to muscle 12 (M12); functions as a repulsive cue inhibiting motoneuron synapse formation on muscle 13 (M13) to guide RP5 and V to the neighboring M12, where its expression is repressed by tey (PubMed:20504957). May also function in embryonic neuronal survival and the synaptic targeting of SNa motoneurons (PubMed:19018662).
Research Articles on TLR-3
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Organs/Tissues associated with TLR-3 elisa kit
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