NP_067642.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,567 Da
NCBI Official Full Name
guanine nucleotide-binding protein subunit beta-4
NCBI Official Synonym Full Names
guanine nucleotide binding protein (G protein), beta polypeptide 4
NCBI Official Synonym Symbols
NCBI Protein Information
guanine nucleotide-binding protein subunit beta-4; transducin beta chain 4; G protein beta-4 subunit
UniProt Protein Name
Guanine nucleotide-binding protein subunit beta-4
UniProt Synonym Protein Names
Transducin beta chain 4
UniProt Entry Name
GBB4_HUMAN
NCBI Summary for GNB4
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. [provided by RefSeq, Jul 2008]
UniProt Comments for GNB4
G-beta 4: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family.
Protein type: Membrane protein, peripheral; G protein, heterotrimeric beta; G protein, heterotrimeric
Chromosomal Location of Human Ortholog: 3q26.33
Cellular Component: lysosomal membrane; plasma membrane
Molecular Function: signal transducer activity; protein complex binding
Biological Process: substantia nigra development; energy reserve metabolic process; signal transduction
Disease: Charcot-marie-tooth Disease, Dominant Intermediate F
Research Articles on GNB4
Precautions
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Disclaimer
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Pathways associated with GNB4 elisa kit
Diseases associated with GNB4 elisa kit
Organs/Tissues associated with GNB4 elisa kit
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