NP_001035536.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
86,148 Da
NCBI Official Full Name
myotubularin-related protein 12 isoform 1
NCBI Official Synonym Full Names
myotubularin related protein 12
NCBI Protein Information
myotubularin-related protein 12; 3-phosphatase adapter protein; 3-phosphatase adapter subunit; phosphatidylinositol-3-phosphate associated protein; phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit; phosphatidylinositol-3 phosphate 3-phosphatase adapter subunit; phosphatidylinositol-3 phosphate 3-phosphatase adaptor subunit
UniProt Protein Name
Myotubularin-related protein 12
UniProt Synonym Protein Names
Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit; 3-PAP; 3-phosphatase adapter protein
UniProt Synonym Gene Names
UniProt Entry Name
MTMRC_HUMAN
NCBI Summary for MTMR12
Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
UniProt Comments for MTMR12
MTMR12: Catalytically inactive phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location. Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold; Protein phosphatase, tyrosine (non-receptor)
Chromosomal Location of Human Ortholog: 5p13.3
Cellular Component: cytoplasm
Molecular Function: protein binding; phosphoric monoester hydrolase activity
Biological Process: dephosphorylation
Research Articles on MTMR12
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Diseases associated with MTMR12 elisa kit
Organs/Tissues associated with MTMR12 elisa kit
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