NP_001265539.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
78,764 Da
NCBI Official Full Name
myb-related protein B isoform 2
NCBI Official Synonym Full Names
v-myb avian myeloblastosis viral oncogene homolog-like 2
NCBI Official Synonym Symbols
NCBI Protein Information
myb-related protein B; myb-like protein 2; v-myb myeloblastosis viral oncogene homolog-like 2
UniProt Protein Name
Myb-related protein B
UniProt Synonym Protein Names
Myb-like protein 2
UniProt Synonym Gene Names
UniProt Entry Name
MYBB_HUMAN
NCBI Summary for MYBL2
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
UniProt Comments for MYBL2
B-Myb: a transcription factor involved in cell cycle progression. Phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
Protein type: DNA-binding; Motility/polarity/chemotaxis; Transcription factor
Chromosomal Location of Human Ortholog: 20q13.1
Cellular Component: nucleoplasm
Molecular Function: protein binding; chromatin binding; transcription factor activity
Biological Process: transcription, DNA-dependent; regulation of cell cycle; positive regulation of transcription from RNA polymerase II promoter; mitotic cell cycle; G2/M transition of mitotic cell cycle
Research Articles on MYBL2
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Products associated with MYBL2 elisa kit
Pathways associated with MYBL2 elisa kit
Diseases associated with MYBL2 elisa kit
Organs/Tissues associated with MYBL2 elisa kit
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