NP_065433.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
103,158 Da
NCBI Official Full Name
adenylate cyclase type 2
NCBI Official Synonym Full Names
adenylate cyclase 2 (brain)
NCBI Official Synonym Symbols
NCBI Protein Information
adenylate cyclase type 2; 3',5'-cyclic AMP synthetase; ATP pyrophosphate-lyase 2; adenylate cyclase II; adenylate cyclase type II; adenylyl cyclase 2; type II adenylate cyclase
UniProt Protein Name
Adenylate cyclase type 2
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 2; Adenylate cyclase type II; Adenylyl cyclase 2
UniProt Synonym Gene Names
UniProt Entry Name
ADCY2_HUMAN
NCBI Summary for ADCY2
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. [provided by RefSeq, Jul 2008]
UniProt Comments for ADCY2
ADCY2: This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Protein type: Adenylyl cyclase; Transporter, aquaporin family; Transporter; Membrane protein, multi-pass; Lyase; Nucleotide Metabolism - purine; EC 4.6.1.1; Membrane protein, integral
Chromosomal Location of Human Ortholog: 5p15.3
Cellular Component: protein complex; membrane; cytoplasm; dendrite; plasma membrane; integral to membrane; intracellular; lipid raft
Molecular Function: protein heterodimerization activity; metal ion binding; G-protein beta/gamma-subunit binding; calcium- and calmodulin-responsive adenylate cyclase activity; ATP binding; adenylate cyclase binding; adenylate cyclase activity
Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; activation of protein kinase A; signal transduction; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; synaptic transmission; phospholipase C activation; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport
Research Articles on ADCY2
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Products associated with ADCY2 elisa kit
Pathways associated with ADCY2 elisa kit
Diseases associated with ADCY2 elisa kit
Organs/Tissues associated with ADCY2 elisa kit
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