EAW98894.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,235 Da
NCBI Official Full Name
transmembrane protein 27
NCBI Official Synonym Full Names
transmembrane protein 27
NCBI Official Synonym Symbols
NCBI Protein Information
collectrin
UniProt Protein Name
Collectrin
UniProt Synonym Protein Names
Transmembrane protein 27
UniProt Entry Name
TMM27_HUMAN
NCBI Summary for TMEM27
This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]
UniProt Comments for TMEM27
TMEM27: Regulator of SNARE complex function. Stimulator of beta cell replication. Belongs to the TMEM27 family.
Protein type: Cell surface; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xp22
Cellular Component: brush border membrane; cytoplasm; integral to membrane
Molecular Function: peptidyl-dipeptidase activity; protein binding; metallopeptidase activity
Biological Process: positive regulation of calcium ion-dependent exocytosis; proteolysis; positive regulation of amino acid transport
Research Articles on TMEM27
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Products associated with TMEM27 elisa kit
Diseases associated with TMEM27 elisa kit
Organs/Tissues associated with TMEM27 elisa kit
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