NP_031911.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
81,604 Da
NCBI Official Full Name
sulfate transporter
NCBI Official Synonym Full Names
solute carrier family 26 (sulfate transporter), member 2
NCBI Official Synonym Symbols
NCBI Protein Information
sulfate transporter; solute carrier family 26 member 2; diastrophic dysplasia protein homolog
UniProt Protein Name
Sulfate transporter
UniProt Synonym Protein Names
Diastrophic dysplasia protein homolog; ST-OB; Solute carrier family 26 member 2
UniProt Synonym Gene Names
UniProt Entry Name
S26A2_MOUSE
UniProt Comments for SLC26A2
SLC26A2: Sulfate transporter. May play a role in endochondral bone formation. Defects in SLC26A2 are the cause of diastrophic dysplasia (DTD). DTD is an autosomal recessive disease characterized by osteochondrodysplasia with clinical features including dwarfism, spinal deformation, and specific joint abnormalities. Defects in SLC26A2 are the cause of achondrogenesis type 1B (ACG1B). ACG1B is a recessively inherited chondrodysplasia characterized by extremely poor skeletal development and perinatal death. Defects in SLC26A2 are the cause of atelosteogenesis type 2 (AO2); also known as neonatal osseous dysplasia 1. AO2 is characterized by severely shortened limbs, small chest, scoliosis, club foot of the equinovarus type (talipes equinovarus), abducted thumbs and great toes, and cleft palate. Patients die of respiratory insufficiency shortly after birth because of the collapse of the airways and pulmonary hypoplasia due to the small rib cage. Defects in SLC26A2 are the cause of multiple epiphyseal dysplasia type 4 (EDM4). EDM is a generalized skeletal dysplasia associated with significant morbidity. Joint pain, joint deformity, waddling gait, and short stature are the main clinical signs and symptoms. EDM is broadly categorized into the more severe Fairbank and the milder Ribbing types. EDM4 is a recessively inherited form, characterized by early childhood-onset hip dysplasia and recurrent patella dislocation. Short stature in EDM4 patients is not frequent. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
Protein type: Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: membrane; integral to membrane
Molecular Function: sulfate transmembrane transporter activity; secondary active sulfate transmembrane transporter activity
Biological Process: ossification; transport; sulfate transport; ion transport; transmembrane transport
Research Articles on SLC26A2
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Pathways associated with SLC26A2 elisa kit
Diseases associated with SLC26A2 elisa kit
Organs/Tissues associated with SLC26A2 elisa kit
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