NP_033547.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
39,659 Da
NCBI Official Full Name
proto-oncogene Wnt-3
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 3
NCBI Official Synonym Symbols
NCBI Protein Information
proto-oncogene Wnt-3; proto-oncogene Int-4; proto-oncogene protein Wnt-3; wingless-related MMTV integration site 3
UniProt Protein Name
Proto-oncogene Wnt-3
UniProt Synonym Protein Names
Proto-oncogene Int-4
UniProt Synonym Gene Names
UniProt Entry Name
WNT3_MOUSE
UniProt Comments for WNT3
WNT3: Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube. Defects in WNT3 are the cause of autosomal recessive tetra-amelia (ARTTRA). Tetra-amelia is a rare human genetic disorder characterized by complete absence of all four limbs and other anomalies such as craniofacial, nervous system, pulmonary, skeletal and urogenital defects. Belongs to the Wnt family.
Protein type: Secreted, signal peptide; Oncoprotein; Secreted
Cellular Component: proteinaceous extracellular matrix; extracellular space; cytoplasm; extracellular region
Molecular Function: protein domain specific binding; protein binding; frizzled binding; receptor binding
Biological Process: limb development; embryonic forelimb morphogenesis; axon guidance; Wnt receptor signaling pathway; multicellular organismal development; cell morphogenesis; dorsal/ventral axis specification; positive regulation of collateral sprouting in the absence of injury; Wnt receptor signaling pathway through beta-catenin; signal transduction; negative regulation of axon extension involved in axon guidance; embryonic hindlimb morphogenesis; Spemann organizer formation at the anterior end of the primitive streak; anterior/posterior pattern formation; limb bud formation; organ morphogenesis; mesoderm formation; cell-cell signaling; gamete generation; anatomical structure formation; anterior/posterior axis specification
Research Articles on WNT3
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Products associated with WNT3 elisa kit
Pathways associated with WNT3 elisa kit
Diseases associated with WNT3 elisa kit
Organs/Tissues associated with WNT3 elisa kit
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