AAK92231.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,681 Da
NCBI Official Full Name
cardiac troponin T
NCBI Official Synonym Full Names
troponin T type 2 (cardiac)
NCBI Official Synonym Symbols
CMH2; RCM3; TnTC; cTnT; CMD1D; CMPD2; LVNC6 [Similar Products]
NCBI Protein Information
troponin T, cardiac muscle; troponin T2, cardiac; cardiomyopathy, hypertrophic 2; cardiomyopathy, dilated 1D (autosomal dominant)
UniProt Protein Name
Troponin T, cardiac muscle
UniProt Synonym Protein Names
Cardiac muscle troponin T; cTnT
UniProt Synonym Gene Names
UniProt Entry Name
TNNT2_HUMAN
NCBI Summary for cTn-T
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for cTn-T
Function: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Research Articles on cTn-T
Precautions
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Disclaimer
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Products associated with cTn-T elisa kit
Pathways associated with cTn-T elisa kit
Diseases associated with cTn-T elisa kit
Disease Name |
Pubmed Publications |
Cardiovascular Diseases Antibodies |
>153 publications with cTn-T and Cardiovascular Diseases |
Heart Diseases Antibodies |
>150 publications with cTn-T and Heart Diseases |
Cardiomyopathies Antibodies |
>115 publications with cTn-T and Cardiomyopathies |
Cardiomyopathy, Hypertrophic Antibodies |
>102 publications with cTn-T and Cardiomyopathy, Hypertrophic |
Cardiomyopathy, Hypertrophic, Familial Antibodies |
>47 publications with cTn-T and Cardiomyopathy, Hypertrophic, Familial |
Cardiomyopathy, Dilated Antibodies |
>44 publications with cTn-T and Cardiomyopathy, Dilated |
Cardiomegaly Antibodies |
>40 publications with cTn-T and Cardiomegaly |
Hypertrophy Antibodies |
>39 publications with cTn-T and Hypertrophy |
Heart Failure Antibodies |
>35 publications with cTn-T and Heart Failure |
Death, Sudden, Cardiac Antibodies |
>33 publications with cTn-T and Death, Sudden, Cardiac |
Organs/Tissues associated with cTn-T elisa kit
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