P33436.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
74,149 Da
NCBI Official Full Name
72 kDa type IV collagenase
NCBI Official Synonym Full Names
matrix metallopeptidase 2
NCBI Protein Information
72 kDa type IV collagenase; MMP-2; gelatinase A; 72 kDa gelatinase; matrix metalloproteinase 2; matrix metalloproteinase-2
UniProt Protein Name
72 kDa type IV collagenase
UniProt Synonym Protein Names
72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2
UniProt Synonym Gene Names
UniProt Entry Name
MMP2_RAT
NCBI Summary for MMP2
plays important roles in wound healing, angiogenesis, platelet aggregation, and tumor metastasis; mediates the response of the intrinsic glomerular mesangial cell to inflammatory stimuli [RGD, Feb 2006]
UniProt Comments for MMP2
Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues ().
Research Articles on MMP2
Precautions
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Disclaimer
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Pathways associated with MMP2 elisa kit
Diseases associated with MMP2 elisa kit
Organs/Tissues associated with MMP2 elisa kit
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