NP_036687.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
50,423 Da
NCBI Official Full Name
protein C-ets-1
NCBI Official Synonym Full Names
v-ets avian erythroblastosis virus E26 oncogene homolog 1
NCBI Protein Information
protein C-ets-1; p54; v-ets erythroblastosis virus E26 oncogene homolog 1; Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1)
UniProt Protein Name
Protein C-ets-1
UniProt Synonym Protein Names
p54
UniProt Synonym Gene Names
UniProt Entry Name
ETS1_RAT
NCBI Summary for ETS1
activates transcription of cyclin-dependent kinase inhibitor p21WAF1/Cip1; plays a role in inhibition of apoptosis [RGD, Feb 2006]
UniProt Comments for ETS1
Ets-1: a proto-oncogenic transcription factor homologous to the v-ets erythroblastosis virus oncogene. The DNA binding activity of Ets1 is controlled by kinases and transcription factors. It contributes to the regulation of cellular differentiation in hematopoietic cells. Ets1 promotes invasive behavior in endothelial cells, vascular smooth muscle cells and epithelial cancer cells. Regulates the expression of MMP1, MMP3, MMP9 and uPA as well as of VEGF and VEGFR gene expression. Two alternatively spliced isoforms have been described.
Protein type: Motility/polarity/chemotaxis; Oncoprotein; Transcription factor; DNA-binding
Cellular Component: nucleoplasm; transcription factor complex; intercellular bridge; cytoplasm; nucleus
Molecular Function: histone acetyltransferase binding; protein binding; DNA binding; sequence-specific DNA binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; hypothalamus development; positive regulation of transcription, DNA-dependent; cell motility involved in cell locomotion; PML body organization and biogenesis; female pregnancy; response to estradiol stimulus; negative regulation of cell cycle; regulation of apoptosis; response to antibiotic; positive regulation of cell proliferation; response to wounding; cell differentiation; immune system process; positive regulation of erythrocyte differentiation; positive regulation of cell motility; angiogenesis involved in wound healing; regulation of angiogenesis; regulation of transcription from RNA polymerase II promoter; positive regulation of angiogenesis; pituitary gland development; response to mechanical stimulus; response to hypoxia; positive regulation of transcription from RNA polymerase II promoter; positive regulation of cell migration
Research Articles on ETS1
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Products associated with ETS1 elisa kit
Pathways associated with ETS1 elisa kit
Diseases associated with ETS1 elisa kit
Organs/Tissues associated with ETS1 elisa kit
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