NP_009206.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,074 Da
NCBI Official Full Name
tumor suppressor candidate 2
NCBI Official Synonym Full Names
tumor suppressor candidate 2
NCBI Protein Information
tumor suppressor candidate 2
UniProt Protein Name
Tumor suppressor candidate 2
UniProt Synonym Protein Names
Fusion 1 protein; Fus-1 protein; PDGFA-associated protein 2
UniProt Synonym Gene Names
UniProt Entry Name
TUSC2_HUMAN
NCBI Summary for TUSC2
This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008]
UniProt Comments for TUSC2
TUSC2: May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells. Belongs to the TUSC2 family.
Protein type: Tumor suppressor
Chromosomal Location of Human Ortholog: 3p21.3
Cellular Component: mitochondrion
Molecular Function: protein binding
Biological Process: cell cycle; cell maturation; cell proliferation; cell-cell signaling; inflammatory response; interleukin-15 production; natural killer cell differentiation; negative regulation of interleukin-17 production; phagocytosis; positive regulation of interleukin-10 production; regulation of mitochondrial membrane potential; response to defense-related host reactive oxygen species production
Research Articles on TUSC2
Precautions
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Disclaimer
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Diseases associated with TUSC2 blocking peptide
Organs/Tissues associated with TUSC2 blocking peptide
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