NP_653132.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,907 Da
NCBI Official Full Name
tribbles homolog 1
NCBI Official Synonym Full Names
tribbles pseudokinase 1
NCBI Protein Information
tribbles homolog 1
UniProt Protein Name
Tribbles homolog 1
UniProt Synonym Gene Names
UniProt Entry Name
TRIB1_MOUSE
UniProt Comments for Trib1
TRB1: Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.
Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; CAMK group; Trbl family
Cellular Component: cytoplasm; nucleus
Molecular Function: ATP binding; mitogen-activated protein kinase kinase binding; protein kinase activity; protein kinase inhibitor activity; transcription factor binding; ubiquitin protein ligase binding; ubiquitin-protein ligase regulator activity
Biological Process: JNK cascade; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of neutrophil differentiation; negative regulation of protein kinase activity; negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; positive regulation of eosinophil differentiation; positive regulation of macrophage differentiation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of ubiquitin-protein ligase activity; protein amino acid phosphorylation; regulation of catalytic activity; regulation of MAP kinase activity; response to lipopolysaccharide
Research Articles on Trib1
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Products associated with Trib1 blocking peptide
Diseases associated with Trib1 blocking peptide
Organs/Tissues associated with Trib1 blocking peptide
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