NP_001021.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36.3 kDa
NCBI Official Full Name
40S ribosomal protein S27
NCBI Official Synonym Full Names
ribosomal protein S27
NCBI Protein Information
40S ribosomal protein S27; metallopanstimulin 1; metallopan-stimulin 1
UniProt Protein Name
40S ribosomal protein S27
UniProt Synonym Protein Names
Metallopan-stimulin 1; MPS-1
UniProt Synonym Gene Names
UniProt Entry Name
RS27_HUMAN
NCBI Summary for RPS27
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
UniProt Comments for RPS27
RPS27: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Protein type: Ribosomal; Translation
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: ribosome; nucleus; cytosol
Molecular Function: protein binding; DNA binding; structural constituent of ribosome; zinc ion binding
Biological Process: SRP-dependent cotranslational protein targeting to membrane; viral reproduction; translation; translational termination; viral infectious cycle; cell proliferation; translational elongation; cellular protein metabolic process; mRNA catabolic process, nonsense-mediated decay; translational initiation; viral transcription; gene expression; mitotic cell cycle
Research Articles on RPS27
Precautions
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Products associated with RPS27 recombinant protein
Pathways associated with RPS27 recombinant protein
Diseases associated with RPS27 recombinant protein
Organs/Tissues associated with RPS27 recombinant protein
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