NP_005682.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
174,425 Da
NCBI Official Full Name
ATP-binding cassette sub-family C member 9 isoform SUR2A
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 9
NCBI Official Synonym Symbols
SUR2; ABC37; CANTU; CMD1O; ATFB12 [Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family C member 9
UniProt Protein Name
ATP-binding cassette sub-family C member 9
UniProt Synonym Protein Names
Sulfonylurea receptor 2
UniProt Synonym Gene Names
NCBI Summary for ABCC9
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]
UniProt Comments for ABCC9
Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Research Articles on ABCC9
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Products associated with ABCC9 recombinant protein
Pathways associated with ABCC9 recombinant protein
Diseases associated with ABCC9 recombinant protein
Organs/Tissues associated with ABCC9 recombinant protein
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