NP_001271120.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
artemin isoform 1
NCBI Official Synonym Full Names
artemin
NCBI Official Synonym Symbols
NCBI Protein Information
artemin
UniProt Protein Name
Artemin
UniProt Entry Name
ARTN_MOUSE
UniProt Comments for ARTN
artemin: Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. Belongs to the TGF-beta family. GDNF subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: extracellular space; extracellular region
Molecular Function: glial cell line-derived neurotrophic factor receptor binding; protein binding; growth factor activity; receptor binding
Biological Process: axon guidance; cell surface receptor linked signal transduction; peripheral nervous system development; induction of positive chemotaxis
Research Articles on ARTN
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Pathways associated with ARTN recombinant protein
Diseases associated with ARTN recombinant protein
Organs/Tissues associated with ARTN recombinant protein
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