NP_665684.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
52,575 Da
NCBI Official Full Name
growth/differentiation factor 10 preproprotein
NCBI Official Synonym Full Names
growth differentiation factor 10
NCBI Official Synonym Symbols
NCBI Protein Information
growth/differentiation factor 10
UniProt Protein Name
Growth/differentiation factor 10
UniProt Synonym Protein Names
Bone morphogenetic protein 3B; BMP-3B
UniProt Synonym Gene Names
NCBI Summary for Gdf10
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein has been shown to promote neural repair after stroke and may act as a tumor suppressor. [provided by RefSeq, Jul 2016]
UniProt Comments for Gdf10
Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway (PubMed:22155034). Plays an inhibitory role in the process of adipogenesis (PubMed:21712809).
Research Articles on Gdf10
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Pathways associated with Gdf10 recombinant protein
Diseases associated with Gdf10 recombinant protein
Organs/Tissues associated with Gdf10 recombinant protein
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