NP_013157.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Erg3p
NCBI Official Synonym Symbols
NCBI Protein Information
Erg3p
UniProt Protein Name
C-5 sterol desaturase
UniProt Synonym Protein Names
Ergosterol Delta(5,6) desaturase; Sterol-C5-desaturase
UniProt Synonym Gene Names
UniProt Entry Name
ERG3_YEAST
UniProt Comments for ERG3
Function: Catalyzes the introduction of a C-5 double bond in the B ring of ergosterol. May contribute to the regulation of ergosterol biosynthesis.
Cofactor: Iron
By similarity.
Pathway: Steroid metabolism; ergosterol biosynthesis; ergosterol from zymosterol: step 3/5.
Subunit structure: Interacts with ERG28. Ref.9
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Probable.
Domain: The histidine box domains may contain the active site and/or be involved in metal ion binding.
Miscellaneous: Present with 36200 molecules/cell in log phase SD medium.
Sequence similarities: Belongs to the sterol desaturase family.
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Products associated with ERG3 recombinant protein
Pathways associated with ERG3 recombinant protein
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