View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List EGF active protein :: Epidermal Growth Factor Active Protein Catalog # MBS650364 Unit / Price 0.1 mg / $445 +1 FREE 8GB USB 0.5 mg / $660 +1 FREE 8GB USB 5x0.5 mg / $2,790 +3 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Epidermal Growth Factor (EGF), Active Protein Popular Item Full Product Name Epidermal Growth Factor, Recombinant, Mouse (EGF, beta-Urogastrone, URG) Product Gene Name EGF active protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sequence NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR Chromosome Location Chromosome: 4; NC_000004.11 (110834040..110934118). Location: 4q25 3D Structure ModBase 3D Structure for Q6QBS2 Host E Coli Purity/Purification Molecular Biology Grade8% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug). Form/Format Supplied as a lyophilized powder from 10mM sodium phosphate, pH 8.2. Reconstitute sterile ddH2O to 0.5-1mg/ml, which can then be further diluted to other aqueous solutions Biological Activity The ED50 as determined by a cell proliferation assay using BALB/c 3T3 cells is 0.1ng/ml, corresponding to a specific activity of 1x10e7 units/mg. Preparation and Storage Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 3 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Active Protein Note Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product. Other Notes Small volumes of EGF active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for EGF active protein Epidermal Growth Factor (EGF) is a polypeptide growth factor which stimulates the proliferation of a wide range of epidermal and epithelial cells. Recombinant murine EGF is a 6.0kD protein containing 53 amino acid residues. Product Categories/Family for EGF active protein Growth Factors; Cytokines; Growth Factors-EGF NCBI/Uniprot data below describe general gene information for EGF. It may not necessarily be applicable to this product. NCBI GI # 46242544 NCBI GeneID 1950 UniProt Primary Accession # Q6QBS2 [Other Products] UniProt Related Accession # P01133; Q6QBS2[Other Products] Molecular Weight 6kD[Similar Products] TOP NCBI Official Full Name epidermal growth factor NCBI Official Synonym Full Names epidermal growth factor NCBI Official Symbol EGF [Similar Products] NCBI Official Synonym Symbols URG; HOMG4 [Similar Products] NCBI Protein Information pro-epidermal growth factor; beta-urogastrone; OTTHUMP00000162922; OTTHUMP00000219721; OTTHUMP00000219722 UniProt Protein Name Epidermal growth factor Protein Family Epidermal growth factor UniProt Gene Name EGF [Similar Products] UniProt Entry Name Q6QBS2_HUMAN TOP NCBI Summary for EGF This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants. TOP Research Articles on EGF 1. Data show that males, but not females, who are A carriers for EGF +61 have an increased risk for developing gastric cancer. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with EGF active protein Reference Product PubMed Publications EGFR active protein >4126 publications with EGF and EGFR ERBB2 active protein >1134 publications with EGF and ERBB2 GRB2 active protein >325 publications with EGF and GRB2 ERBB3 active protein >217 publications with EGF and ERBB3 Pathways associated with EGF active protein Products by Pathway Pathway Diagram Arf6 Signaling Events Pathway antibodies Arf6 Signaling Events Pathway Diagram Bladder Cancer Pathway antibodies Bladder Cancer Pathway Diagram Bladder Cancer Pathway antibodies Bladder Cancer Pathway Diagram Ceramide Signaling Pathway antibodies Ceramide Signaling Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Cytokine-cytokine Receptor Interaction Pathway antibodies Cytokine-cytokine Receptor Interaction Pathway Diagram Delta-Notch Signaling Pathway antibodies Delta-Notch Signaling Pathway Diagram EGF Receptor (ErbB1) Signaling Pathway antibodies EGF Receptor (ErbB1) Signaling Pathway Diagram EGFR Downregulation Pathway antibodies EGFR Downregulation Pathway Diagram EGFR Interacts With Phospholipase C-gamma Pathway antibodies EGFR Interacts With Phospholipase C-gamma Pathway Diagram Diseases associated with EGF active protein Disease Name Pubmed Publications Neoplasms Antibodies >6899 publications with EGF and Neoplasms Breast Neoplasms Antibodies >1366 publications with EGF and Breast Neoplasms Adenocarcinoma Antibodies >1086 publications with EGF and Adenocarcinoma Carcinoma, Squamous Cell Antibodies >1034 publications with EGF and Carcinoma, Squamous Cell Cell Transformation, Neoplastic Antibodies >777 publications with EGF and Cell Transformation, Neoplastic Neoplasms, Experimental Antibodies >716 publications with EGF and Neoplasms, Experimental Lung Neoplasms Antibodies >580 publications with EGF and Lung Neoplasms Drug Toxicity Antibodies >560 publications with EGF and Drug Toxicity Head and Neck Neoplasms Antibodies >546 publications with EGF and Head and Neck Neoplasms Neoplasm Metastasis Antibodies >455 publications with EGF and Neoplasm Metastasis Organs/Tissues associated with EGF active protein Organ/Tissue Name Pubmed Publications Brain Antibodies >1523 publications with EGF and Brain Kidney Antibodies >1438 publications with EGF and Kidney Lung Antibodies >1356 publications with EGF and Lung Skin Antibodies >1184 publications with EGF and Skin Muscle Antibodies >1159 publications with EGF and Muscle Embryonic Tissue Antibodies >997 publications with EGF and Embryonic Tissue Mouth Antibodies >808 publications with EGF and Mouth Intestine Antibodies >805 publications with EGF and Intestine Eye Antibodies >790 publications with EGF and Eye Placenta Antibodies >430 publications with EGF and Placenta TOP © 2006-24 MyBioSource.com. 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