NP_001081076.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,485 Da
NCBI Official Full Name
forkhead box protein A4-B
NCBI Official Synonym Full Names
forkhead box A4 S homeolog
NCBI Official Synonym Symbols
fkh1; XFD-1; XFKH1; FoxA4a; fkh1-A; foxa4b; xkfh-1; foxa4-a; foxa4-b; pintallavis [Similar Products]
NCBI Protein Information
forkhead box protein A4-B
UniProt Protein Name
Forkhead box protein A4-B
UniProt Synonym Protein Names
Fork head domain-related protein 1'; FKH-1; Forkhead protein 1; xFD-1'; xFKH1
UniProt Synonym Gene Names
fkh1; FoxA4-B; FoxA4b; FKH-1; Forkhead protein 1; xFD-1'; xFKH1 [Similar Products]
UniProt Comments for foxa4-b
Transcriptional repressor involved in embryonic nervous system development. Plays a role in the induction and patterning of the anterior-posterior neural axis. Involved in the establishment of floor plate differentiation from neural plate cells during gastrulation. Binds the anf1 promoter sequence to restrict expression of anf1 to the anterior of the neural plate, thereby patterning the forebrain. Can bind to the HNF-3-alpha DNA target sequence. Cooperates with t/bra in a dose-dependent manner to specify dorsal mesoderm formation, including notochord. May be involved in the dorso-ventral patterning of the mesoderm. Binds to DNA via the target sequence 5'-[GA]TAAA[TC]A-3', with 5'-GTAAATA-3' being the preferred binding site ().
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Organs/Tissues associated with foxa4-b recombinant protein
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