NP_006490.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,397 Da
NCBI Official Full Name
galectin-8 isoform a
NCBI Official Synonym Full Names
lectin, galactoside-binding, soluble, 8
NCBI Protein Information
galectin-8; Po66 carbohydrate binding protein; galectin 8; galectin-8g; po66 carbohydrate-binding protein; prostate carcinoma tumor antigen 1
UniProt Protein Name
Galectin-8
UniProt Synonym Protein Names
Po66 carbohydrate-binding protein; Po66-CBP; Prostate carcinoma tumor antigen 1; PCTA-1
UniProt Synonym Gene Names
UniProt Entry Name
LEG8_HUMAN
NCBI Summary for LGALS8
This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for LGALS8
LGALS8: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion
Chromosomal Location of Human Ortholog: 1q43
Cellular Component: extracellular space; membrane; cytoplasm
Molecular Function: protein binding; carbohydrate binding
Biological Process: plasma cell differentiation; T cell costimulation
Research Articles on LGALS8
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Diseases associated with LGALS8 active protein
Organs/Tissues associated with LGALS8 active protein
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