NP_005802.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
45,091 Da
NCBI Official Full Name
growth/differentiation factor 11
NCBI Official Synonym Full Names
growth differentiation factor 11
NCBI Protein Information
growth/differentiation factor 11
UniProt Protein Name
Growth/differentiation factor 11
UniProt Synonym Protein Names
Bone morphogenetic protein 11; BMP-11
UniProt Synonym Gene Names
UniProt Entry Name
GDF11_HUMAN
UniProt Comments for GDF11
GDF11: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Belongs to the TGF-beta family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q13.2
Cellular Component: extracellular space; intracellular membrane-bound organelle; nucleoplasm; protein complex
Molecular Function: cytokine activity; transforming growth factor beta receptor binding
Biological Process: cell development; mesoderm development; nervous system development; regulation of apoptosis; regulation of MAPKKK cascade; skeletal development
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Diseases associated with GDF11 recombinant protein
Organs/Tissues associated with GDF11 recombinant protein
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