View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List HIV-1 p55 gag Recombinant Protein Catalog # MBS142616 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name HIV-1 p55 gag, Recombinant Protein Popular Item Full Product Name Recombinant HIV-1 p55 gag Product Synonym Names HIV-1 p55 gag; HIV-1 p55 gag Recombinant; HIV-1 p55 gag Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Host Baculovirus Insect Cells Specificity Immunoreactive with sera from HIV infected individuals. Purity/Purification Greater than 90.0% as determined by HPLC analysis & SDS-PAGE. Form/Format The HIV-1 p55 gag protein solution contains 10mM Tris pH 8, 140mM NaCl and 400mM L-Arginine.Sterile filtered colorless clear solution. Concentration 75 ug/ml (lot specific) Preparation and Storage Recombinant HIV -1 p55 although stable at 4 degree C for 3 weeks, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles. Other Notes Small volumes of HIV-1 p55 gag recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for HIV-1 p55 gag recombinant protein Description: HIV-1 p55 Recombinant- is a 55kDa protein derived from gag gene of an HTLV-3/LAV isolate of HIV-1. The HIV-1 p55 is glycosylated with N-linked sugars and produced using baculovirus vectors in insect cells. The full length authmentic p55 gag protein forms particles within iteself of approximately 23nm in size (as determind by electron particles).Introduction: Human immunodeficiency virus (HIV) is a retrovirusthat can lead to a condition in which the immune systembegins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the humanimmune systemsuch as helper T cells(specifically CD4+ T cells), macrophagesand dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosisin infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytesthat recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunityis lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry of the target cell, the viral RNA genomeis converted to double-stranded DNAby a virally encoded reverse transcriptasethat is present in the virus particle. This viral DNA is then integrated into the cellular DNA by a virally encoded integraseso that the genome can be transcribed. Once the virus has infected the cell, two pathways are possible: either the virus becomes latentand the infected cell continues to function, or the virus becomes active and replicates, and a large number of virus particles are liberated that can then infect other cells. Product Categories/Family for HIV-1 p55 gag recombinant protein Viral Antigens; HUMAN IMMUNODEFICIENCY VIRUS; Viral Antigens; HIV Applications Tested/Suitable for HIV-1 p55 gag recombinant protein ELISA (EIA), Western Blot (WB) Application Notes for HIV-1 p55 gag recombinant protein HIV-1 p55 gag antigen is suitable for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP