NP_004125.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
73,680 Da
NCBI Official Full Name
stress-70 protein, mitochondrial
NCBI Official Synonym Full Names
heat shock 70kDa protein 9 (mortalin)
NCBI Official Synonym Symbols
CSA; MOT; MOT2; GRP75; PBP74; GRP-75; HSPA9B; MGC4500; MTHSP75 [Similar Products]
NCBI Protein Information
stress-70 protein, mitochondrial; mortalin-2; p66-mortalin; OTTHUMP00000159494; mortalin, perinuclear; heat shock 70kD protein 9B; peptide-binding protein 74; 75 kDa glucose-regulated protein
UniProt Protein Name
Stress-70 protein, mitochondrial
UniProt Synonym Protein Names
75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; MOT; Peptide-binding protein 74
UniProt Synonym Gene Names
UniProt Entry Name
GRP75_HUMAN
NCBI Summary for HspA9
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.
UniProt Comments for HspA9
HSPA9B: Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone. Interacts with FXN. Interacts with HSCB. Component of the MINOS/MitOS complex, that includes IMMT, HSPA9 and CHCHD3 and associates with mitochondrial outer membrane proteins SAMM50, MTX1 and MTX2. Belongs to the heat shock protein 70 family.
Protein type: Heat shock protein; Chaperone; Nucleolus
Chromosomal Location of Human Ortholog: 5q31.1
Cellular Component: focal adhesion; mitochondrion; cytoplasm; nucleolus
Molecular Function: protein binding; ubiquitin protein ligase binding; unfolded protein binding; ATP binding
Biological Process: cellular protein metabolic process; protein folding; protein export from nucleus; protein targeting to mitochondrion; negative regulation of apoptosis
Research Articles on HspA9
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Products associated with HspA9 recombinant protein
Pathways associated with HspA9 recombinant protein
Diseases associated with HspA9 recombinant protein
Organs/Tissues associated with HspA9 recombinant protein
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