NP_001138783.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
55,990 Da
NCBI Official Full Name
perilipin-1
NCBI Official Synonym Full Names
perilipin 1
NCBI Protein Information
perilipin-1
UniProt Protein Name
Perilipin-1
UniProt Synonym Protein Names
Lipid droplet-associated protein
UniProt Synonym Gene Names
NCBI Summary for PLIN1
The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009]
UniProt Comments for PLIN1
Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.
Research Articles on PLIN1
Precautions
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Disclaimer
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Products associated with PLIN1 recombinant protein
Pathways associated with PLIN1 recombinant protein
Diseases associated with PLIN1 recombinant protein
Organs/Tissues associated with PLIN1 recombinant protein
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