NP_001025
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47.0 kDa (409aa) confirmed by MALDI-TOF
NCBI Official Full Name
ribonucleoside-diphosphate reductase subunit M2 isoform 2
NCBI Official Synonym Full Names
ribonucleotide reductase regulatory subunit M2
NCBI Protein Information
ribonucleoside-diphosphate reductase subunit M2
UniProt Protein Name
Ribonucleoside-diphosphate reductase subunit M2
UniProt Synonym Protein Names
Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit
UniProt Synonym Gene Names
NCBI Summary for RRM2
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009]
UniProt Comments for RRM2
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
Product References and Citations for RRM2 recombinant protein
Torrents E, et al. (2002) J Mol Evol. 55 (2):138-52; Herrick J,et al. (2007) Mol Microbiol. 63 (1):22-34;
Research Articles on RRM2
Precautions
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Disclaimer
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Products associated with RRM2 recombinant protein
Pathways associated with RRM2 recombinant protein
Diseases associated with RRM2 recombinant protein
Organs/Tissues associated with RRM2 recombinant protein
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