NP_001812.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
74,071 Da
NCBI Official Full Name
rab proteins geranylgeranyltransferase component A 2
NCBI Official Synonym Full Names
CHM like, Rab escort protein 2
NCBI Official Synonym Symbols
NCBI Protein Information
rab proteins geranylgeranyltransferase component A 2
UniProt Protein Name
Rab proteins geranylgeranyltransferase component A 2
UniProt Synonym Protein Names
Choroideremia-like protein; Rab escort protein 2; REP-2
UniProt Synonym Gene Names
NCBI Summary for CHML
The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina. CHML is localized close to the gene for Usher syndrome type II. [provided by RefSeq, Jul 2008]
UniProt Comments for CHML
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
Research Articles on CHML
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Products associated with CHML recombinant protein
Diseases associated with CHML recombinant protein
Organs/Tissues associated with CHML recombinant protein
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