P83719.1
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UniProt Primary Accession #
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NCBI Official Full Name
Ranacyclin-T
UniProt Protein Name
Ranacyclin-T
UniProt Entry Name
RACYT_RANTE
UniProt Comments for RNCT
Function: Has antibacterial activity against Gram-positive bacteria B.megaterium Bm11, S.lentus and M.luteus, and Gram-negative bacteria E.coli D22, Y.pseudotuberculosis YP III and P.syringae pv tabaci, and antifungal activity against C.albicans 10231, C.tropicalis, C.guiller-mondii and P.nicotianae spores. Has weak hemolytic activity. The mature peptide inserts into the hydrophobic core of the bacterial cell membrane and increases permeability without disrupting membrane integrity. Probably binds to the outer membrane surface before aggregating to form transmembrane pores. Ref.1
Subcellular location: Secreted
By similarity UniProtKB P83663.
Tissue specificity: Expressed by the skin granular glands. Ref.1
Sequence similarities: Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
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Products associated with RNCT recombinant protein
Pathways associated with RNCT recombinant protein
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