NP_001019636
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24.4kDa (219aa), confirmed by MALDI-TOF.
NCBI Official Full Name
superoxide dismutase
NCBI Official Synonym Full Names
superoxide dismutase 2
NCBI Official Synonym Symbols
IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD [Similar Products]
NCBI Protein Information
superoxide dismutase [Mn], mitochondrial
UniProt Protein Name
Superoxide dismutase [Mn], mitochondrial
NCBI Summary for SOD2
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016]
UniProt Comments for SOD2
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Product References and Citations for SOD2 active protein
MacMillan-Crow L.A., et al. (1999) Arch. Biochem. Biophys. 366:82-88; Prunotto M, et al. (2010) J Am Soc Nephrol. 21 (3):507-19.;
Research Articles on SOD2
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Disclaimer
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Products associated with SOD2 active protein
Pathways associated with SOD2 active protein
Diseases associated with SOD2 active protein
Organs/Tissues associated with SOD2 active protein
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