NP_033432.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
40.1 kDa
NCBI Official Full Name
troponin I, cardiac muscle
NCBI Official Synonym Full Names
troponin I, cardiac 3
NCBI Official Synonym Symbols
NCBI Protein Information
troponin I, cardiac muscle; cardiac troponin I
UniProt Protein Name
Troponin I, cardiac muscle
UniProt Synonym Protein Names
Cardiac troponin I
UniProt Entry Name
TNNI3_MOUSE
UniProt Comments for Tnni3
TNNI3: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Binds to actin and tropomyosin. Interacts with TRIM63. Interacts with STK4/MST1. Belongs to the troponin I family.
Protein type: Motility/polarity/chemotaxis; Actin-binding; Motor
Cellular Component: sarcomere; troponin complex; myofibril; contractile fiber; cell; cytoplasm
Molecular Function: troponin T binding; troponin C binding; protein domain specific binding; metal ion binding; calcium channel inhibitor activity; actin binding; protein kinase binding; calcium-dependent protein binding
Biological Process: regulation of smooth muscle contraction; cellular calcium ion homeostasis; striated muscle contraction; heart contraction; regulation of muscle contraction; heart development; regulation of systemic arterial blood pressure by ischemic conditions; ventricular cardiac muscle morphogenesis; vasculogenesis; negative regulation of ATPase activity; cardiac muscle contraction
Research Articles on Tnni3
Precautions
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Disclaimer
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Products associated with Tnni3 recombinant protein
Pathways associated with Tnni3 recombinant protein
Diseases associated with Tnni3 recombinant protein
Disease Name |
Pubmed Publications |
Cardiovascular Diseases Antibodies |
>70 publications with Tnni3 and Cardiovascular Diseases |
Heart Diseases Antibodies |
>69 publications with Tnni3 and Heart Diseases |
Cardiomyopathies Antibodies |
>61 publications with Tnni3 and Cardiomyopathies |
Cardiomyopathy, Hypertrophic, Familial Antibodies |
>25 publications with Tnni3 and Cardiomyopathy, Hypertrophic, Familial |
Cardiomyopathy, Dilated Antibodies |
>18 publications with Tnni3 and Cardiomyopathy, Dilated |
CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 7 Antibodies |
>9 publications with Tnni3 and CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 7 |
Cardiomyopathy, Restrictive Antibodies |
>8 publications with Tnni3 and Cardiomyopathy, Restrictive |
Nervous System Diseases Antibodies |
>5 publications with Tnni3 and Nervous System Diseases |
Cardiomyopathy, Familial Restrictive, 1 Antibodies |
>3 publications with Tnni3 and Cardiomyopathy, Familial Restrictive, 1 |
Hypertension Antibodies |
>3 publications with Tnni3 and Hypertension |
Organs/Tissues associated with Tnni3 recombinant protein
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