View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Rat anti-Mouse CD23 (Fc epsilon RII) Monoclonal Antibody Catalog # MBS673270 Unit / Price 0.1 mg / $315 +1 FREE 8GB USB 5x0.1 mg / $1,250 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name CD23 (Fc epsilon RII), Monoclonal Antibody Full Product Name Rat Anti-Mouse CD23/FCeRII-PE/Cy7 Product Synonym Names Rat Anti-Mouse CD23/FCeRII - Phycoerythrin-Labeled/Cy7; Rat Anti-Mouse CD23 (Fc epsilon RII) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype Rat IgG2a kappa Clone Number 2G8 Host Rat Species Reactivity Mouse Specificity CD23 low affinity IgE Fc receptorThe CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments.^1 It is expressed on most mature, conventional B cells (but not on peritoneal CD5^+ B cells), and can also be found on the surface of T cells, macrophages and platelets.^1-6 It is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation.^3 The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors.^2-6 CD23 has been described as a "membrane bound cytokine," in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro.^6 Form/Format R - phycoerythrin - Cyanine 7 (R - PE - CY7) Conjugate Characterization To ensure lot-to-lot consistency, each batch of monoclonal antibody is tested by flow cytometry to conform to characteristics of a standard reference reagent. Representative data are included in this product insert. Preparation and Storage The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The allophycocyanin (APC) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! R-phycoerythrin-Cyanine 7 (R-PE-CY 7) conjugates are supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 degree C. Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 degree C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed. Other Notes Small volumes of anti-CD23 (Fc epsilon RII) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Applications Tested/Suitable for anti-CD23 (Fc epsilon RII) antibody Flow Cytometry; Immunoprecipitation Application Notes for anti-CD23 (Fc epsilon RII) antibody Research Application(s): Differentiation of B cell subpopulations by cell sortingFlow Cytometry Suggested Dilution: <= 0.1 ug/10^6 cells TOP Product References and Citations for anti-CD23 (Fc epsilon RII) antibody 1. Rao, M., W. Lee, and D. Conrad. 1987. J. Immunol. 138:1845.2. Cong Y.Z., Rabin E. and Wortis H.H. 1991. International Immunology. 3:467.3. Conrad DH. 1991. Monographs in Allergy. 29:9.4. Vercelli D.and Geha RS. 1989. Annals of Allergy. 63:4.5. Yu, P., Kosco-Vilbios, M., Richards, M., Kohler, G. and Lamers, M.C. 1994. Nature 369:753.6. Bonnefoy, J.-Y., Lecoanet-Henchoz, S., Aubry, J.P., Gauchat, J.F. and Graber, P. 1995. Current Opinions in Immunol. 7:355. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP