BC015018
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
249,491 Da
NCBI Official Full Name
Homo sapiens dedicator of cytokinesis 10, mRNA
NCBI Official Synonym Full Names
dedicator of cytokinesis 10
NCBI Protein Information
dedicator of cytokinesis protein 10
UniProt Protein Name
Dedicator of cytokinesis protein 10
UniProt Synonym Protein Names
Zizimin-3
UniProt Synonym Gene Names
UniProt Entry Name
DOC10_HUMAN
NCBI Summary for DOCK10
This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2014]
UniProt Comments for DOCK10
DOCK10: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Belongs to the DOCK family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q36.2
Cellular Component: membrane
Biological Process: regulation of cell migration
Research Articles on DOCK10
Precautions
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Disclaimer
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Pathways associated with DOCK10 cdna clone
Diseases associated with DOCK10 cdna clone
Organs/Tissues associated with DOCK10 cdna clone
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